In the paper Human blood Fifa 14 Ultimate Team Coins metabolite

In the paper Human blood Fifa 14 Ultimate Team Coins metabolite timetable indicates internal bodytime, Ueda and his team explain how they trialled thetheory with six volunteers over a two week period at a sleep lab.Conditions were carefully controlled, including light and roomtemperature, and the subjects were not allowed to know the time buttold when to eat and sleep. Every two hours, blood samples wereretrieved from the subjects via a catheter. On day one and thefinal day of the study, each participant was asked to spend 39hours in a reclining chair. The team then compared samples takenduring the first 39 hours from the three volunteers whose rhythmsexhibited the most similarities and found 4,000 altered molecules,with 58 demonstrating particularly strong and regular troughs andpeaks. After comparing these against the final 39 hours, the teamwas able to plot out a timetable that was reliable to within threehours, sometimes two, of the subjects' body clock. The 58 hormones,fats and amino acids were then used as markers to predict theinternal rhythms of the other three volunteers -- this was achievedwith the same accuracy by analysing the levels of those metabolitesin just two blood samples taken 12 hours apart. The markers, thepaper argues, are the ideal indicators for mapping out a timetablesince the metabolites chosen oscillated independently of theindividual, food intake, sleep, light, and temperature.

The study calls the discovery a convenient diagnostic tool --this is in contrast to the method of measuring melatonin levelsfrom blood samples taken every hour over a 24-hour period. However,it studies the samples using liquid chromatography-massspectrometry, a method not used commercially in hospitals. Byapplying the timetable approach, it is certainly more accurate thanthe melatonin method, however its accuracy levels have already beencalled into question.

The range of error is nothing to brag about for a system withinherent precision measured in minutes, Michael Terman, apsychiatrist from Columbia University who specialises in bodyclocks, told Discover Magazine.

Ueda is working on improving the system's accuracy, however, bywidening the pool of test subjects. He hopes to reduce the bloodsamples needed to just one, to make it even more efficient than the24-hour system in place which, though less invasive that themelatonin test, takes just as much time to complete.